Clinical trials of cannabinoid drugs for symptom. The National Academies report found pot use likely increases the risk of dependence on other substances, including tobacco. It called for heavier investment in research on the biology of cannabinoid systems, careful clinical studies of cannabinoids in clinical syndromes, analysis of cannabinoids' psychological effects on symptoms, and evaluations of the health consequences of heavy marijuana use recommends against the use of smoked marijuana in medicine and for the development of a medical cannabinoid inhaler and recommends that compassionate use of marijuana be considered under carefully reviewed protocols. According to the 2018 National Institute on Drug Abuse (NIDA) Monitoring the Future Survey (MTF), daily, past month, past year, and lifetime marijuana use among 8 th graders has declined, and. The individual health risks of smoking marijuana should be studied. The report used scientific reviews, public hearings, and reports from other agencies, and was evaluated by knowledgeable advisors and reviewers. Washington, DC: The National Academies Press. PUBMED Abstract National Academies of Sciences, Engineering, and Medicine: The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research. In response to public pressure to allow the medical use of marijuana, the Office of National Drug Control Policy, Washington, DC, funded a study by the Institute of Medicine evaluating the scientific evidence for benefits and risks of using marijuana as a medicine. The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research(link is external). The association between marijuana smoking and lung cancer: a systematic review.